Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling
Gastric and small intestinal organoids differentiated from human pluripotent stem cells (hPSCs) have revolutionized the
Efficient CNS targeting in adult mice by intrathecal infusion of single-stranded AAV9-GFP for gene therapy of neurological disorders
Adeno-associated virus (AAV) gene therapy constitutes a powerful tool for the treatment of neurodegenerative diseases.
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
The enteric nervous system (ENS) of the gastrointestinal tract controls many diverse functions, including motility
Enriching a cellulose hydrogel with a biologically active marine exopolysaccharide for cell-based cartilage engineering
The development of biologically and mechanically competent hydrogels is a prerequisite in cartilage engineering. We
Innovative strategies for intervertebral disc regenerative medicine: From cell therapies to multiscale delivery systems
As our understanding of the physiopathology of intervertebral disc (IVD) degeneration has improved, novel therapeutic
Long-term neurologic and cardiac correction by intrathecal gene therapy in Pompe disease
Pompe disease is a lysosomal storage disorder caused by acid-α-glucosidase (GAA) deficiency, leading to glycogen