Bone remodeling and biomaterials research group
Repair medicine
Tools for Restorative and Regenerative Medicine

Research themes of the GEROM unit

1) Bone fragility in secondary osteoporosis (immobilization, hypokinesia, diabetes) and therapeutic strategies of bone fragility

2) Bone reactions in contact with orthopedic prostheses and osteonecrosis

3) Therapeutic strategies – Bone biomaterials for filling bone defects (β-TCP, hydroxyapatite and biological polymers). LabCom ANR NextBone


Bone diseases, implants, prostheses,  biomaterials for bone grafs, 3D microarchitecture, 2D and 3D histomorphometry, IR and Raman microscopy

Material available in the unit

Microtomography and nanotomography for 3D analysis of biomaterials
Bone histomorphometry
Raman and InfraRed microscopy
Measurement of bone quality and biomaterials

2 Polycut S-bone microtomes
Microtomy equipment for hard objects (metals, phospho-calcic biomaterials) diamond saw and Struers polishing machines
Microtome  for Large and hard objects (Metals) Diamond Band Saw and Exakt Digital Polishing system.

Leica cell time-laps station (videomicroscopy) for cell cultures on biomaterials, Roper software (Metamorph software)
Photon Microscopy, Fluorescence, Polarization (7 units)
Vertical Interferential Microscopy (surface analysis, profilometry)
Autoprobe Atomic Force Microscope CP  Veeco / Bruker (surface analysis)
Raman Microspectroscopy and imaging (Qontor Renishaw)
Fourier Transform Infrared Microscopy FTIRI (Hyperion Bruker)
Electrospinning apparatus YFlow for nanofiber preparation
CSM nanoindenter
Instron 5942 (Instron, France) for biomechanics
X vivo microtomograph (microscanner-X Skyscan 1272) with 3D reconstruction station
In vivo X-ray microtomograph (microscanner-X Skyscan 1076) with ECG monitoring and respiration
Nantotom Nanotomograph (Phoenix, General Electric) + 3D reconstruction station
Digital radiography (Faxitron).