Therassay Preclinical Therapeutic Assay
Tools for Restorative and Regenerative Medicine


Therassay is a functional exploration core facility for small animals in the field of cardiovascular, metabolic, neuromuscular, digestive, respiratory and cancerous pathologies.  Therassay  provides  to  academic  and  industrial  teams  technical  resources  and  scientific  expertise  to  analyze  new  therapeutic  pathways in pathophysiology. It is also for the drug or food industry to provide scientific evidence of health effects of their ingredients, extracts or food supplements.


Specific technologies

In vivo tests

  • Vascular exploration
  • Cardiac exploration
  • Pulmonary exploration
  • Cancerogenesis
  • Motor exploration
  • Digestive exploration


Ex vivo

  • Isolated organs bath (Gastrointestinal contractility, Cardiac contractility, Contractility of vascular rings on intact or beta-escin permeabilized vascular smooth muscle strips)
  • Ussing chamber (Evaluation of paracellular gastrointestinal permeability)
  • Isolated working heart



  • Separation of lipoproteins by FPLC
  • Sterols and biliary acids analysis in plasma or feces by mass spectrometry analysis (GC/MS)
  • Biomarkers quantification
  • Haematology
  • Luminex® technology



  • Microtom (HS355S)
  • Spin tissue processor (STP 120) (Process biological specimens from chemical fixation to paraffin infiltration)
  • Coloration baths (x16)

 Collaboration modalities

The platform is accessible to academic research units and companies.


  • R&D projects and functional exploration in small animals
  • Provision of equipments (on line booking, technical support, in course training)
  • Value creation, education, animation